DISORDER OF LYMPH AND SPLEEN - 1ST PRACTICAL CLASS (HISTO)

SILA RUJUK BUKU - PRACTICAL HISTOPATHOLOGY.

1)Non-caseating granuloma (early TB) -page 17

·        Multiple granuloma

·        Large langerhan cells (giant cells)

·        Separated by lymphocytes

2) Caseating tuberculus lymphadenitis (late TB) - page 18

·        Caseation

·        No structure

VIDEO

3) Small lymphocytic lymphoma (non-Hodgkin)

·        Monotonous with small lymphocytes

·        No follicle

4)Adenocarcinoma metastasis (page 40)

·        Contain gland (usually no gland)

·        Perinodal fat (at the side)

·        Deep blue

                        
















thx to SUFIAH MANAN DAN SITI NABILA

DISORDER OF LYMPH AND SPLEEN - 1ST PRACTICAL CLASS (GROSS)

Bilharzial splenomegaly (page 128)

Organ : Spleen

Description :

·         A hugely enlarged spleen. The enlargement is uniform, retaining its shape.

·         Consistency : Firm ( Marked congestion )

·         Color : Deep red

·         Capsule : Thickened & grayish white due to fibrosis

·         Perisplenitis : Patchy. Occur over areas of subcapsular haemorrhage & heals by fibrosis forming slightly raised white patches.

Milliary Tuberculosis – Spleen (page 131)

 

Organ : Spleen

Description :

·         Enlarged

·         Cut section : 1 ) Studded with numerous tubercles distributed all over the spleen, but more condensed near the periphery

                      2 ) Multiple yellow caseating tubercles with central cavitation

·         Tubercles :

1.       Rounded

2.       Soft

3.       Showing central yellow cheesy necrotic tissue

Lymphoma of the spleen - page 132-133

 

Organ : Spleen

Description :

·         Enlarged

·         Cut section : Large well circumscribed grayish white well defined non – encapsulated tumor formed of multiple coalescent nodules

·         Tumor : Shows foci of necrosis

Tuberculous lymphadenitis - page 134

 

Organ : Lymph nodes

Description :

·         Group of lymph nodes – Enlarged & matted together

·         Cut surface : Show numerous areas of yellowish cheese like necrotic tissue

Lymphoma ( Hodgkin’s ) page 135

Organ : Lymph nodes

Description :

·         Group of lymph nodes – Enlarged , firm & discrete

·         Lymph nodes – Variable in size , smooth surface

·         Cut surface : Tan – coloured with foci of necrosis

TSPECIAL THX TO Areqa Arsof n Iezzaty Md Shah

LYMPH NODE DISORDER - videos

for us to understand this chapter, so i found these videos that may help.

akusectiondua

Selamat datang kawan2, rasanya blog ni belum dirasmikan secara rasmi. Jadi ni ade sedikit pesanan penaja lah lebih kurang. Buat pengenalan, bagi yang tak tahu, blog ini dikhaskan sebagai tempat studi untuk subjek Pathology dan Human Right. seiring dengan tanggungjawab kami memegang subjek tersebut. insyaAllah kami akan memanfaatkan blog ini sebaik mungkin untuk dimanfaatkan oleh rakan2 seperjuangan yang lain.

untuk pengetahuan kawan2, ape yang akan ada dalam blog ini adalah

1. segala nota dan rujukan untuk belajar subjek ini mengikut silibus yang telah ditetapkan. eg. nota, buku rujukan, web link dan sebagainya.
2. quiz dan soalan2 yang berkaitan. untuk dijawab oleh anda semua sejurus habis belajar. terus ulangkaji dan uji diri anda!!
3. segala infomasi berkenaan exam, kelas, perubahan waktu untuk subjek2 ini. eg: soalan apa yang akan keluar, soalan spot dan dsb.
4. semua gambar-gambar dan description untuk kelas praktikal. patho histo dan patho gross. juga rujukan dan soalan.
5. berkongsi cara yang lebih efektif dan menarik untuk belajar pathology dan human right. insyaAllah dapat membantu

Jadi, apa yang saya ingin nyatakan idsini ialah, dengan adanya blog ini, kami harap dapat menolong dan membantu anda sedikit sebanyak dalam subjek yang telah diamanahkan kepada kami. Seperti yang kita tahu, AIM atau SASARAN paling penting pagi pihak2 SR tahun ini adalah REPEAT SIFAR. sebagaimana yang kita maklum juga, tahun ni merupakan tahun paling kritikal bagi kita kerana kita akan melangkah ke tahun empat, memerlukan tiada 'carry' subjek atau fail ! jadi sasaran kami ialah tidak mahu andaikata benda/kisah ini terjadi, lebih2 lagi membawa subjek pathilogy dan human right. insyaAllah, berkat usaha dan doa yang telah kita lakukan, kita akan mendapat kejayaan dan dipermudahkan hidup.

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SPLEEN DISORDER - Quizes

1.       All of the following are mild splenomegaly EXCEPT

A.      -Acute splenitis

B.     - Infectious mononucleosis

C.     - Amyloidosis

D.    -  Acute splenic congestion

2.       The syndrome of hypersplenism is characterized by all of the following EXCEPT

A.     - Correction of the cytopenia by surgical removal of the spleen

B.     - Splenomegaly

C.      -Reduction in blood elements

D.      -Infections

3.       In congestive splenomegaly, grossly the spleen is …………………………… especially in …………………

The cut surface is……………………………

4.       True or false

                                 i.            In nonspecicific  acute splenitis, it occurs in the course of acute systemic viral infection( )

                               ii.            Metastatic deposits are common in splenic neoplasms and are usually found only in advanced malignancy (  )

                              iii.            Rupture of the spleen is followed by severe intraperitoneal hemorrhage and treated by surgical removal of spleen (  )

                             iv.            Clinically, splenic infarct may cause sudden left upper hypochondrial pain (  )

DISORDER OF SPLEEN - Notes

 LYMPH NODE DISORDER. u can refer to systemic pathology part 2 page 210-212. 

causes of spleenomegaly

spleenic neoplasm
hypersplenism
rupture of spleen (causes)

LYMPH NODE DISORDER- Quizes

PATHOLOGY

Questions regarding Lymph Node Disorders

1.       Tonsilitis and tooth infection are type of

A.      Generalized acute nonspecific lympadenitis

B.      Chronic non the specific lymphadenitis

C.      Localized acute nonspecific lymphadenitis

D.      Chronic nonspecific lympadenitis

2.       Which of the following is not part of Chronic specific lymphadenitis

A.      Tuberculosis

B.      Infectious mononucleosis

C.      Sarcoidosis

D.      Syphilis

3.       Paracortical lymphoid hyperplasia caused by

A.      Organisms that activate B-cells

B.      Microbiologic agents particularly viruses or organisms that stimulate T-cells

C.      Draining of cancer

D.      Drains a focus of infection

4.       Sinus histiocytosis characterized by ……………………………………………………………………………….

5.       ………………………………….. represent an immune response to the Tumour or its products.

6.       ....................................characeterized by morphologically by the presence of distinctive neoplastic giant cells, Reed-Sternberg  cells.

7.       According to Rye classification, Hodgkin’s Lymphoma is classified microscopically into 4 subtypes which are

                                 i.            ………………………………

                               ii.            ……………………………..

                              iii.            ……………………………..

                             iv.            ……………………………..

8.       Which of the following are mmore common in women

A.      Hodgkin’s lymphoma lymphocytic depletion

B.      Hodgkin’s lymphoma mixed cellularity

C.      Hodgkin’s lymphoma lymphocyte predominance

D.      Hodgkin’s lymphoma nodular sclerosis

9.       According to Ann Arbor Classification, involvement of two or more lymph node regions on the same side of the diaphragm alone  or with involvement of limited contiguous extralymphatic organ or tissues is classified into:

A.      Stage IV

B.      Stage III

C.      Stage II

D.      Stage I

10.   True or false

                                 i.            NHL characterized by presence of Reed-Sternberg cells and inflammatory cells (    )

                               ii.            HL spreads by contiguity                                                                                                  (   )

                              iii.            HL characterized by presence of systemic manifestations                                         (   )  

                             iv.            In NHL Waldeyer’s ring and mesenteric lymph nodes are not commonly involved (   )

                               v.            NHL more frequent involvement of multiple peripheral lymph nodes   (   )



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LYMPH NODE DISORDER

below are notes from our friends in chapter : LYMPH NODE DISORDER. u can refer to systemic pathology part 2 page 199-210. hope these note can help u guys studying for becoming exam.

classification of lymphoma and Rye's classifiacation of Hodgkin's Lymphomas

non hodgkin's lymphoma n morphology

degree of malignancy, fuctional cell types,
burkitss lymphoma
mycosis fungoides and sezary syndrome.

REAL notes
clinical picture
pathological complication

different between HL n NHL
etiology and pathogenic factors
different between leukemia n lymphoma

Rye's classification table.
appearance n
clinical picture

staging system and clinical stage of lymphoma.

welcome~

section 2, with lots of LOVE !